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  • Nephrotic syndromes

    12:00 AM | November 30, -0001Author: Adeleke

    Key finding is proteinuria greater than 3.5 g/24hrs generalized pitting edema and acites due to hypoalbuminemia, and spontanteous peritonitis (strep pnemo); hypertension in some types; hypercoaguable states due to loss of antithrombin III, hypercholesterContinue reading →

  • Membranous glomerulonephritis

    12:00 AM | November 30, -0001Author: Adeleke

    NEPHROTIC:MCC of nephritic syndrome in adults; Drugs captopril; infx with HBV, plasmodium malaria, syphillis; Malignancy: carcinomas non-hodkins lymphoma; Autoimmune disease; SLE LM: diffues thickening of memebranes EM: silver stain show spike and domeContinue reading →

  • Minimal change disease

    12:00 AM | November 30, -0001Author: Adeleke

    NEPHROTIC:negative IF, EM shows fusion of podocytes and no deposits; T cell cytokines cause the GBM to lose its negative charge; selective proteinuria (albumin and globins), often preceeded by respiratory infxn or routine immunization; structurally ... Continue reading →