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IL-4 and IL-13, secreted by TH2 cells
12:00 AM | November 30, -0001Author: Adeleke
stimulate B lymphocytes to switch to IgE-producing cells.Continue reading
Archives
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Histamine
12:00 AM | November 30, -0001Author: Adeleke
causes the dilatation of blood vessel, increases vascular permeability; & stimulates the contraction of smooth musclesContinue reading
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Leukotrienes
12:00 AM | November 30, -0001Author: Adeleke
Smooth muscle contraction, increase vascular permeability, and mucus secretion. (similar to histamine, but in the later stages)Continue reading
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PAF
12:00 AM | November 30, -0001Author: Adeleke
chemotactic for leukocytes, and activation of neutrophil, eosinophil, and plateletContinue reading
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Platelet Activating Factor
12:00 AM | November 30, -0001Author: Adeleke
increased vascular permeability, vasodilation; also, adhesion of PMNs to endothelial cells (recruitment)Continue reading
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Prostaglandins
12:00 AM | November 30, -0001Author: Adeleke
vasodilation, edema; made by cyclo-oxygenases (COX enzymes)Continue reading
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IL-3, IL-5, GM-CSF
12:00 AM | November 30, -0001Author: Adeleke
promote eosinophil production and activationContinue reading
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TNF-a
12:00 AM | November 30, -0001Author: Adeleke
promotes inflammation, stimulate cytokine productionContinue reading