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What is Orotic Acid involved in?
12:00 AM | November 30, -0001Author: Adeleke
Pyrimidine synthesisContinue reading
Archives
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What is the additional AA that is used to make purines?
12:00 AM | November 30, -0001Author: Adeleke
GlycineContinue reading
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What enzyme in Purine synthesis is the rate-limiting step? What (2) drugs inhibit this step?
12:00 AM | November 30, -0001Author: Adeleke
PRPP Amidotransferase Drugs ("Purin"): AlloPURINol (Gout); 6-MercaptoPURINe (cancer)Continue reading
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Lack of the salvage pathway of purines leads to what syndrome? What is the missing enzyme? What is an unusual sign of this syndrome?
12:00 AM | November 30, -0001Author: Adeleke
LNS = Lacks Nucleotide Salvage: Lesch-Nyhan syndrome HGPRTase Sign: Self-mutilationContinue reading
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Adenosine Deaminase deficiency causes a lack of what product?
12:00 AM | November 30, -0001Author: Adeleke
InosineContinue reading
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Dx: 48-yo man w/ recessive condition is at high risk for deep vein thrombosis and has had replacement of ectopic lenses; no evidence of anemia. Enzyme that is deficient? What AA would be in excess?
12:00 AM | November 30, -0001Author: Adeleke
Homocysteinuria Enzyme: Cystathionine Synthase AA: MethionineContinue reading
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Dx: Man has dark pigment of cartilage and arthritis, and dark urine What enzyme is deficient?
12:00 AM | November 30, -0001Author: Adeleke
Alkaptouria Enzyme: Homogentisate Oxidase [AL KAPT a HOMe]Continue reading
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How do you treat Cystinuria?
12:00 AM | November 30, -0001Author: Adeleke
Alkalinize the urine w: AcetazolamideContinue reading
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Precursor to Ketone body formation
12:00 AM | November 30, -0001Author: Adeleke
HMG-CoAContinue reading