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Inactivation suppressor genes
12:00 AM | November 30, -0001Author: Adeleke
majority are point mutations; loss of suppressionContinue reading
Archives
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Sporadic retinoblastoma
12:00 AM | November 30, -0001Author: Adeleke
two hit theory; two separate point mutations of RB suppressor gene onContinue reading
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AD retinoblastoma
12:00 AM | November 30, -0001Author: Adeleke
one hit theory; one already inactivated in germ cellsContinue reading
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TP53 suppressor gene functions
12:00 AM | November 30, -0001Author: Adeleke
G,-S phase inhibition, DNA repair, activation BAX apoptosis geneContinue reading
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Inactivation TP 53 suppressor gene
12:00 AM | November 30, -0001Author: Adeleke
inactivation causes majority of human cancersContinue reading
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RB suppressor gene function
12:00 AM | November 30, -0001Author: Adeleke
G1-S phase inhibitionContinue reading
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Inactivation RB suppressor gene
12:00 AM | November 30, -0001Author: Adeleke
retinoblastoma, osteogenic sarcomaContinue reading
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APC suppressor gene function
12:00 AM | November 30, -0001Author: Adeleke
prevents nuclear transcription by cateninContinue reading
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Inactivation APC suppressor gene
12:00 AM | November 30, -0001Author: Adeleke
familial polyposis (FAP)Continue reading
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BRCA1/2 suppressor genes function
12:00 AM | November 30, -0001Author: Adeleke
DNA repair InactivationContinue reading