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Diffusion defect
12:00 AM | November 30, -0001Author: Adeleke
O2 cannot cross alveolar-capillary interface; interstitial lung disease (e.g., sarcoidosis)Continue reading
Archives
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Methemoglobin
12:00 AM | November 30, -0001Author: Adeleke
↓ SaO2; heme Fe+3; oxidizing agents (sulfur/nitro drugs); Rx with IV methylene blueContinue reading
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Clinical methemoglobinemia
12:00 AM | November 30, -0001Author: Adeleke
cyanosis not corrected by O2; chocolate colored bloodContinue reading
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Carbon monoxide
12:00 AM | November 30, -0001Author: Adeleke
↓ SaO2; left-shift O2 binding curve; inhibits cytochrome oxidaseContinue reading
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Causes carbon monoxide poisoning
12:00 AM | November 30, -0001Author: Adeleke
car exhaust, space heaters, smoke inhalationContinue reading
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S/S carbon monoxide poisoning
12:00 AM | November 30, -0001Author: Adeleke
headache; cherry red color skinContinue reading
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Cyanide
12:00 AM | November 30, -0001Author: Adeleke
inhibits cytochrome oxidase; systemic asphyxiantContinue reading
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Carbon monoxide + cyanide poisoning
12:00 AM | November 30, -0001Author: Adeleke
house firesContinue reading
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Left-shifted O2 curve
12:00 AM | November 30, -0001Author: Adeleke
↓ 2, 3 BPG, carbon monoxide, alkalosis, HbF, methemoglobin, hypothermiaContinue reading
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Right-shifted O2 curve
12:00 AM | November 30, -0001Author: Adeleke
↑ 2, 3 BPG, high altitude, acidosis, feverContinue reading